Home | Screening data | Screen comparisons | Search for compounds | Structure search


SONAR Targetspace for Z-score NB
Targetspace hs
Targetspace hs pval
XgmmL File for compound
Stats file for targetspace
Targetspace Analysis
Dataset submitted

Dynamic Data Scan For Putative Targets (genetic,physical,all)
Prediction Returned Rows:36
Sym Orf Description Function No All Z_score hyperg
PKC1 YBL105C Protein serine/threonine kinase essential for cell wall remodeling during growth...   20 102   0.0044
CDC28 YBR160W Catalytic subunit of the main cell cycle cyclin-dependent kinase (CDK); alternat... cyclin-dependent protein kinase 18 110   0
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p), a transcriptional activa... transcription factor 16 140   0
CWH41 YGL027C Processing alpha glucosidase I, ER type II integral membrane N-glycoprotein invo... glucosidase I 16 62   0.0659
BNI4 YNL233W Targeting subunit for Glc7p protein phosphatase, localized to the bud neck, requ... scaffold protein 14 41   NAN
RVS161 YCR009C Amphiphysin-like lipid raft protein; subunit of a complex (Rvs161p-Rvs167p) that...   14 140   0
CHS3 YBR023C Chitin synthase III, catalyzes the transfer of N-acetylglucosamine (GlcNAc) to c... chitin synthase 3 14 93   NAN
BCK2 YER167W Protein rich in serine and threonine residues involved in protein kinase C signa...   13 47   0
CLN1 YMR199W G1 cyclin involved in regulation of the cell cycle; activates Cdc28p kinase to p... G1 cyclin 13 84   0
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase, functionally redundant with alt... 1,3-beta-D-glucan synthase 12 126   0
ROT2 YBR229C Glucosidase II catalytic subunit required for normal cell wall synthesis; mutati... glucosidase II 12 92   0.1064
ROT1 YMR200W Protein that may be involved in cell wall function; mutations in rot1 cause cell... membrane protein (putative) 12 27   0
CNB1 YKL190W Calcineurin B; the regulatory subunit of calcineurin, a Ca++/calmodulin-regulate... calcineurin regulatory B subunit|type 2B protein phosphatase 10 81   0
  YKL037W     10 12   0.0015
FPS1 YLL043W Plasma membrane glycerol channel, member of the major intrinsic protein (MIP) fa... glycerol channel protein 10 28   0.0012
  YKL161C     10 5   0.1116
CCW12 YLR110C Cell wall protein, mutants are defective in mating and agglutination, expression... cell wall mannoprotein 10 115   0.0014
CHS5 YLR330W Protein of unknown function, involved in chitin biosynthesis by regulating Chs3p...   10 107   0
MYO2 YOR326W One of two type V myosins, involved in polarized distribution of mitochondria; r... class V myosin 10 104   0
MID2 YLR332W O-glycosylated plasma membrane protein that acts as a sensor for cell wall integ...   10 46   0.0018
PTC1 YDL006W Type 2C protein phosphatase (PP2C); inactivates the osmosensing MAPK cascade by ...   10 64   0.0942
KRE11 YGR166W Protein involved in biosynthesis of cell wall beta-glucans; subunit of the TRAPP...   10 62   0
PPZ1 YML016C Serine/threonine protein phosphatase Z, isoform of Ppz2p; involved in regulation...   10 31   0.1159
PPZ2 YDR436W Serine/threonine protein phosphatase Z, isoform of Ppz1p; involved in regulation...   10 10   0.1342
SIW14 YNL032W Tyrosine phosphatase that plays a role in actin filament organization and endocy... tyrosine phosphatase 10 16   0
TPM1 YNL079C Major isoform of tropomyosin; binds to and stabilizes actin cables and filaments... tropomyosin I 10 46   0
RVS167 YDR388W Actin-associated protein, subunit of a complex (Rvs161p-Rvs167p) involved in reg... cytoskeletal protein (putative) 10 108   0
RPI1 YIL119C Putative transcriptional regulator; overexpression suppresses the heat shock sen... ras inhibitor 10 9   0.0011
KAR1 YNL188W Essential protein involved in karyogamy during mating and in spindle pole body d...   10 16   0.0029
YUR1 YJL139C Mannosyltransferase of the KTR1 family, involved in protein N-glycosylation; loc... mannosyltransferase 10 29   0.0013
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis; proposed to be involv... 57 kDa nuclear protein 10 145   NAN
RIM101 YHL027W Transcriptional repressor involved in the response to pH; required for alkaline ...   10 65   0.1272
SPA2 YLL021W Component of the polarisome, which functions in actin cytoskeletal organization ...   10 54   0
SSD1 YDR293C Protein with a role in maintenance of cellular integrity, interacts with compone...   9 72   0.1027
ZDS1 YMR273C Protein that interacts with silencing proteins at the telomere, involved in tran...   9 39   0.0491
WHI3 YNL197C RNA binding protein that binds to and sequesters the G1 cyclin CLN3 mRNA; regula... RNA binding protein (putative) 9 22   0

Service provided by the Mike Tyers Laboratory